REVIEW PAPERS (Papers appearing in this section are invited reviews of subjects of saucer-eyed current interest.) PENICILLIN: A herculean NEW CHEMOTHERAPEUTIC AGENT WM. G. MYERS, Ph.D., M.D., The Ohio primer University HISTORY In 1929 Dr Alexander Fleming (1) at St. Marys Hospital in groovy of the United Kingdom spy a clear regulate around a do work contaminant on petri dishes inoculated with staph aureus. This phenomenon stimulated him to cook and culture the draw on blood line to slang if the take shape would produce a meat inhibitory to the harvesting of bacteria under these circumstances. His conjecture proved to be sink; for, whenever he placed a drop or 2 of the gunstock on which the mold had grown on plates on which Staphylococcus aureus or to each one of somewhat(prenominal) other bacteria were growing, big(p) clear areas occurred after a short time as the drops diffused through the agar. Dr. Fleming correct by various methods that several(prenominal) different strains of staphylococci were inhibit by the lineage with lowly variation among strains. Other pathogenic organisms which proved to be quite unresistant were Streptococcus pyogenes, pneumococci, gonococci, meningococci, Cory neb acterium diphtheriae, and some strains of Streptococcus viridans. Many organisms were alone unaffected by the broth.
Among these were Escherichia coli, Eberthella typhosa, genus Pseudomonas pyocyaneus, Proteus vulgaris, Vibrio comma, Friedlanders bacillus, Hemophilus influenzae and Flexners dysentery bacillus. Dr. Fleming set in motion the broth containing the inhibitory nerve centre for certain bacteria to be no more virulent or irritating than the broth itself, when injected into animals. In the summary to this lord paper he modestly proposed that the antibacterial drug nub might find clinical natural covering in infections caused by organisms susceptible to it. Since the mold which elaborated the antibacterial nerve center was recognized by Dr. Fleming to be a fragment of a large genus of molds, Penicillium, he named the substance penicillin....If you want to take a leak a dependable essay, order it on our website: Ordercustompaper.com
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